Naloxone HCL – Opioid Overdose Reversal

What It Is

• Generic Name: Naloxone Hydrochloride (HCL).
• Drug Class: Opioid antagonist.
• Brand Names: Narcan, Kloxxado, Zimhi, RiVive.
• Forms: Injectable (IV, IM, SC) and nasal spray.

• Opioid Overdose: Quickly reverses life‑threatening respiratory depression.
• Emergency Situations: Used when patients show slowed breathing, unconsciousness, or severe sleepiness.
• Hospital Use: Sometimes given after surgery to counteract opioid pain medication side effects.

How It Works

• Naloxone competes with opioids at receptor sites in the brain.
• It displaces opioids like heroin, morphine, oxycodone, or fentanyl.
• Effects occur within 2–5 minutes and last 30–90 minutes, sometimes requiring repeat doses.

Availability

• Injectable Solutions: 0.4 mg/mL, 1 mg/mL, 2 mg/mL vials.
• Nasal Sprays: 4 mg or higher doses for layperson use.
• Access: Prescription and increasingly over‑the‑counter (OTC) in many countries.

Risks & Precautions

• Withdrawal Symptoms: In opioid‑dependent patients, naloxone can trigger acute withdrawal (nausea, sweating, agitation).
• Short Duration: Opioid effects may outlast naloxone, requiring repeated administration.
• Safe Profile: Generally well tolerated; essential in emergency overdose kits.

Package Quantity: 10/Pkg
Strength: 0.4 mg/ml Strength
Generic Name: 10 vials Injection, USP
Total Volume: 1 ml
Compare To: Narcan
Container Type: Single Dose Vial, Glass Fliptop Vial
Non-DEHP: Non-DEHP
Cap Color: Orange – Injection USP, NARCAN.

Single Dose Vial, Glass Fliptop Vial
10 vials Injection is indicated for the complete or partial reversal of opioid depression, including respiratory depression, induced by natural and synthetic opioids including propoxyphene, methadone, and certain mixed agonist-antagonist analgesics: nalbuphine, pentazocine, butorphanol and cyclazocine.

Package Quantity: 10/Pkg
Strength: 0.4 mg/ml Strength
Generic Name: Injection, USP
Total Volume: 1 ml
Compare To: Narcan
Container Type: Single Dose Vial, Glass Fliptop Vial
Non-DEHP: Non-DEHP
Cap Color: Orange

Naloxone HCL 10 vials – Injection USP, NARCAN.

Single Dose Vial, Glass Fliptop Vial
Naloxone HCL 10 vials Injection is indicated for the complete or partial reversal of opioid depression, including respiratory depression, induced by natural and synthetic opioids including propoxyphene, methadone, and certain mixed agonist-antagonist analgesics: nalbuphine, pentazocine, butorphanol and

10 vials cyclazocine.