Stresnil 100ml – Vet Ranch Supply

What is Stresnil?

Stresnil 100ml is a veterinary injectable solution containing Azaperone, a butyrophenone derivative with sedative and tranquilizing properties. It is widely used in veterinary medicine to calm animals, reduce aggression, and facilitate safe handling during stressful situations such as transport, medical procedures, or group housing.

How Stresnil Works

Azaperone acts on the central nervous system by:

• Reducing aggression and excitability in animals.
• Inducing mild to moderate sedation, making handling safer.
• Lowering stress responses, especially during transport or medical interventions.
• Supporting smoother recovery after procedures requiring restraint.

Its effects typically begin within minutes of injection and last for several hours, depending on dosage and species.

Veterinary Applications

Stresnil 100ml is commonly prescribed for:

• Pigs: To reduce aggression in group housing, facilitate transport, and calm animals during veterinary procedures.
• Horses: Occasionally used to manage stress or aggression during handling.
• Exotic Animals: Applied in zoological settings to sedate animals for safe management.

Benefits of Stresnil

• Improves animal welfare by reducing stress and aggression.
• Facilitates safe handling for veterinarians and caretakers.
• Supports transport and group housing with fewer injuries.
• Reliable onset and duration, making it predictable for veterinary use.

Risks & Considerations

As with all sedatives, Stresnil must be used responsibly:

• Prescription‑only: Requires veterinary supervision.
• Species‑specific dosing: Overdosing can cause excessive sedation or side effects.
• Not for food‑producing animals in certain jurisdictions due to withdrawal times.
• Possible side effects: Hypotension, drowsiness, or altered behavior.

Because of these risks, Stresnil should only be administered by or under the guidance of a licensed veterinarian.

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STRESNIL 100ML Treatment and prevention of aggressiveness.
Stress inhibition (anxiety and nervousness), preventing the struggles that ensue when mixing or regrouping pigs.
Cardiac overload
Transportation of boars and breeders, provided that this is not at the slaughterhouse.
Preanesthetic in major surgery.
Immobilizer in minor surgery.
Reduction of the excitation of sows during childbirth and lactation, as well as aggressiveness against piglets.
Effect of demolition and immobilization.

Active Ingredient: Azaperone

Species: Pigs

Presentations:

STRESNIL 100ML is a neuroleptic belonging to the butyrophenone class, with specific use in pigs. It produces a predictable psychomotor sedation after intramuscular administration, with no signs of narcosis. After administration the animals become quiet and indifferent to the environment. The degree of sedation is dependent on the dose administered. Adult animals need comparatively lower doses compared to growing animals. In small doses (0.5 mg / kg) the animals are slightly sedated, but can be easily managed. At increasing doses the animals become heavier, and slower in movements at 2 mg / kg the animal falls in decubitus and remains immobile / lying about 2 hours, and ceases to be aggressive. The induction period is short. The maximum effect is reached 15 minutes after administration in young animals and 30 minutes in adult animals. The duration of action is 1-3 hours and depends on the dose and weight of the animal. After treatment the animal should be left alone, in a quiet environment. If the animal is disturbed or agitated during the induction period, the results obtained may be unsatisfactory.

INDICATIONS, DOSAGE AND ROUTE
(S) OF ADMINISTRATION Aggressive sows (which do not accept newborn piglets, do not allow them to suck or bite them) 1ml / 20kg. Sows will accept newborn piglets 1 / 2-1 hours after treatment and may even accept piglets from other sows. For the administration, a calm and slow approach of the animal is necessary in order not to scare him. The indicated dose should be strictly observed. If the doses are too small, the aggression is reduced only temporarily. If the doses are too high, the animals will relapse after waking up.

SPECIES FOR STRESNIL 100ML
PIGS.

OBSTETRICAL INTERVENTIONS: 1ml / 20kg in case of termination of parturition due to excitation, in case of assisted parturition (manual extraction of piglets), in case of exaggerated contractions, or for correction of vaginal or uterine prolapse.

CARDIACA OVERLOAD (tachycardia, high pulse) 1ml / 100kg. The animal calms down within minutes of administering the product. The tremors decrease and the respiratory movements decrease in frequency and increase in amplitude. Cyanosis gradually decreases and the pulse slows down. It is very important that treatment is instituted immediately.

TRANSPORTATION OF PICKED PIGS: 0.4 mg / kg to 2 mg / kg (1 ml / 100 kg to 1 ml / 20 kg). A dose of 0.4 mg / kg, injected 15-30 minutes before transport, reduces mortality and weight loss during transport. The dose can be increased up to 2 mg / kg to prevent fights during transport. The animals must have sufficient space to lie down and the truck must have adequate ventilation. The effect of the product lasts up to 2-3 hours after injection.
TRANSPORT OF THE SWEETS: dose: 1 mg / kg (0.5 ml / 20 kg).
The animals are injected about half an hour before loading. During the induction period, the animals should be kept separately. The animals remain drowsy for about two to three hours after the injection.
Not more than 1 mg / kg will be injected. Overdose can induce penis relaxation, which can lead to injury. Prevention and control of aggression and post-regrouping fights 2 mg / kg (1 ml / 20 kg).

Pigs from different nests or boxes should be brought together in a box immediately after the injection of Stresnil. After only a few minutes, they will sleep together, regardless of their origin. Subsequently, no more violent struggles occur. However, all animals must be treated. The indicated dose should be observed. If the dose is too low, the animals will be sedated but the aggression will not be faded, or it will only be temporarily diminished. The shelter (hall) must be closed during the day of treatment. The still unmated boars can be slightly aggressive after “awakening”. If necessary, a further dose of should be given. Usually, after that, the animals will remain completely decubbed. Newly weaned piglets can be Stresnil injected with STRESNIL 100MLupon arrival in the fattening unit.Animal fights will calm down shortly after Stresnil injection. Animals will no longer fight even when the effect of the product has disappeared.
Premedication with local and general anesthesia: 1 to 2 mg / kg IM (0.5 to 1 ml / 20 kg).
When STRESNIL 100ML is used for general anesthesia, the dose of the anesthetic should be reduced due to the potentiating effect of STRESNIL 100ML. If the results are insufficient, the injection technique (deep intramuscular injections) and the accuracy of the dose used should be reconsidered.
For all indications, the injection is given strictly intramuscularly behind the ear. A long hypodermic needle should be used and the injection should be as close as possible behind the ear and perpendicular to the skin. If heavy, corpulent animals are injected into the cervical region using a short needle, there is a risk of injecting some of the drug into the fat layer. In this case, the injection may have insufficient effect. If insufficient results are obtained, the injection technique (deep intramuscular injections, behind the ear) and the accuracy of the dose used should be reconsidered.

CONTRAINDICATIONS
Due to possible tissue residues, the use of Stresnil is contraindicated for the transport or regrouping of the pigs to be slaughtered within seven days after treatment. The use of Should be avoided in a very cold environment due to the potential for risk of cardiovascular collapse due to peripheral vasodilation.

SIDE EFFECTS o
None. If you notice any serious reactions or other effects not mentioned in this leaflet, please inform your veterinarian.

SPECIAL PRECAUTIONS FOR USE IN ANIMALS
In animals, the dose of 1 mg / kg should not be exceeded.
Use during pregnancy, lactation:
At the therapeutic dose, Stresnil has no adverse effect on the mechanism of parturition, lactation or maternal instinct. STRESNIL 100ML can be used in pregnant animals and during the lactation period. Interactions with other medicinal products or other forms of interaction:
When Stresnil is used as a premedication to produce general anesthesia, the dose of the anesthetic should be reduced due to the potentiating effect of STRESNIL 100ML.

OVERDOSAGE STRESNIL 100ML (symptoms, emergency procedures, antidotes):
Salivation and breathing may occur if overdose occurs. These manifestations disappear spontaneously and do not lead to further conditions. In boars, penile relaxation may occur after a dose exceeding 1 mg / kg. This can result in penile lesions.

INCOMPATIBILITIES STRESNIL 100ML
Do not mix with any other medicine in the same syringe.

WAITING TIME for STRESNIL 100ML
Meat and organs: 7 days.

Responsible Veterinary Sedation

Stresnil 100ml is a trusted veterinary sedative used to reduce stress and aggression in pigs, horses, and exotic animals. While highly effective, it requires strict veterinary supervision to ensure safe and appropriate use.