Pentosan Injection 250mg/ml, 50ml – Advanced Osteoarthritis Therapy for Horses

Introduction: Long-Term Joint Care for Equine Athletes

Osteoarthritis and degenerative joint disease are common causes of pain, stiffness, and reduced performance in horses. Pentosan Injection 250mg/ml, 50ml is a concentrated anti-inflammatory and cartilage stimulant designed to actively repair, protect, and rejuvenate joints. Unlike traditional NSAIDs or corticosteroids, Pentosan promotes healing rather than simply masking pain.

Composition

• Active Ingredient: Sodium Pentosan Polysulfate (PPS) 250mg/ml
• Origin: PPS is a linear polymer prepared from beechwood xylan, refined to reduce anticoagulant effects while enhancing anti-inflammatory, fibrinolytic, and tissue-protective properties.

Features & Benefits

1. Stimulates Cartilage Repair
   • Activates chondrocyte metabolism, increasing proteoglycan and cartilage matrix production.
   • Enhances synovial fluid quality and viscosity for better lubrication and stabilization.
2. Potent Anti-Inflammatory Action
   • Inhibits mediators of the arachidonic acid cascade.
   • Blocks enzymes that degrade cartilage matrix components, preserving joint integrity.
3. Fibrinolytic & Lipolytic Effects
   • Promotes dissolution of fibrin deposits in synovial tissues.
   • Mobilizes lipids and cholesterol in joint blood vessels, improving circulation and healing.
4. Safe Alternative to NSAIDs
   • Does not suppress cartilage repair.
   • Provides long-term improvement rather than short-term symptom relief.

Indications

• Non-infectious inflammatory joint disease
• Traumatic arthritis
• Osteoarthritis
• Degenerative cartilaginous joint disease
• Osteochondrosis dessicans

Dosage & Administration

• IV Injection: 3mg/kg bodyweight (1.5g for a 500kg horse) at 5–7 day intervals for four injections.
• IA Injection: 1ml sterile intra-articular injection.
• Treatment Course: Four injections provide sustained improvement for up to six months.
• Additional Use: Safe to administer further injections if soreness recurs.
• Synergy: Works particularly well with Cosequin Equine (Glucosamine + Chondroitin sulfate) for joint repair.

Presentation

• 50ml sterile single-dose glass vial
• Equivalent to 1.5g for a 500kg horse (6ml) at 5–7 day intervals

Storage

• No refrigeration required
• Store below 25°C and protect from light

Contraindications

Do not use in horses with:

• Clotting defects or traumatic hemorrhage
• Active infection
• Renal or hepatic failure
• Within 48 hours of surgery

Restoring Mobility & Comfort in Horses

Pentosan Injection 250mg/ml, 50ml is a sophisticated approach to equine joint care, offering anti-inflammatory relief while actively stimulating cartilage repair. Trusted by veterinarians, it provides long-term improvement in mobility, comfort, and performance.