Prosolvin – Vet Ranch Supply
What is Prosolvin?
Prosolvin is a veterinary injectable solution containing Luprostiol, a synthetic prostaglandin analogue. It is formulated to regulate reproductive cycles in cattle, pigs, and horses, making it a key tool in modern veterinary reproductive management.
How Prosolvin Works
- Luprostiol mimics natural prostaglandins, inducing luteolysis (breakdown of the corpus luteum).
- This leads to a return to oestrus and subsequent ovulation.
- By controlling timing, veterinarians can synchronize groups of animals for planned breeding programs.
Veterinary Applications
- Cattle:
- Oestrus control in cows and heifers.
- Synchronization of breeding cycles in herds.
- Ovulation typically occurs 2–4 days after treatment.
- Horses:
- Induces oestrus within 5 days.
- Ovulation follows 2–4 days later.
- Pigs:
- Used in reproductive management programs.
Benefits of Prosolvin
- Improves breeding efficiency by synchronizing cycles.
- Reduces labor costs in herd management.
- Predictable ovulation timing for planned insemination.
- Trusted veterinary formulation with proven efficacy.
Risks & Considerations
- Prescription‑only: Requires veterinary supervision.
- Species‑specific dosing: Incorrect use may reduce efficacy.
- Possible side effects: Mild local reactions at injection site.
- Compliance required: Must follow reproductive program protocols.
Vet Ranch Supply – Trusted Source
At Vet Ranch Supply, we provide secure online shopping, fast worldwide delivery, and veterinary‑approved products. Customers in the UK, Canada, Australia, Germany, France, Switzerland, Spain, Portugal, and across Europe rely on us for trusted animal health solutions.
We emphasize compliance, transparency, and customer support, ensuring that products like Prosolvin are used responsibly and effectively.
contains 7.5mg Luprostiol in each mL of clear injectable solution. Luprostiol is a potent synthetic analogue of the natural prostaglandin, PGF2α, for use in horses and cattle.
Prosolvin has fewer adverse reactions than natural prostaglandins, such as sweating and colic. Because of its better duration of activity, one single injection of Prosolvin® is enough to be effective. The mean plasma half-life is 70 minutes, much longer than natural prostaglandins. Because of this long half-life and its high safety, Prosolvin® is an obvious choice in the management of reproduction in mares.
In mares Prosolvin can be used for the induction of a second heat after foaling, the treatment of a persistent corpus luteum, synchronization of oestrus, treatment of pyometra and endometritis, induction of abortion and the induction of parturition. Prosolvin is effective in mares for the stimulation of fertile oestrus, termination of pregnancy following foetal death, termination of pseudo-pregnancy and treating anoestrus during lactation.
Prosolvin can also be used in cattle for oestrus control, treatment of sub-oestrus, and the treatment of chronic endometritis, pyometra and mummified or macerated foetuses.
The activity of Prosolvin is focused on the genital tract. Therefore, it has very low effect on the digestive smooth muscles, which explains its high safety. This advantage is crucial in horses, which are very sensitive to the side effects of prostaglandins.
The high safety of Prosolvin is due to its higher affinity to prostaglandins receptors on corpus luteum for luteolysis and its slower degradation in lungs leading to a longer action.
It contains 7.5mg Luprostiol in each mL of clear injectable solution. Luprostiol is a potent synthetic analogue of the natural prostaglandin, PGF2α, for use in horses and cattle.
It has fewer adverse reactions than natural prostaglandins, such as sweating and colic. Because of its better duration of activity, one single injection is enough to be effective. The mean plasma half-life is 70 minutes, much longer than natural prostaglandins. Because of this long half-life and its high safety, Prosolvin® is an obvious choice in the management of reproduction in mares.
In mares Prosolvin can be used for the induction of a second heat after foaling, the treatment of a persistent corpus luteum, synchronization of oestrus, treatment of pyometra and endometritis, induction of abortion and the induction of parturition. Prosolvin is effective in mares for the stimulation of fertile oestrus, termination of pregnancy following foetal death, termination of pseudo-pregnancy and treating anoestrus during lactation.
Reproductive Management Made Easy
Prosolvin is a synthetic prostaglandin veterinary injection designed to regulate oestrus and synchronize breeding cycles in cattle, pigs, and horses. By providing predictable ovulation timing, it helps veterinarians and breeders improve reproductive efficiency and herd management.
Vet Ranch Supply ensures that customers worldwide can access Prosolvin safely, securely, and with confidence in product quality.

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