Previcox

Previcox is a highly selective non-steroidal anti-inflammatory drug for dogs with the unique active ingredient firocoxib in tablet form. The most selective COX-2 inhibitor, which provides excellent results. Safe for long-term use. Fast-acting, within 15 minutes after the first dose. Powerful pain relief 24 hours a day without “failure” in pain relief. Steady increase in the degree of improvement of parameters during long-term treatment. Leads to an improvement noticeable to dog owners. Higher level of improvement compared with NSAIDs with a predominant anti-inflammatory effect. Provides global control of osteoarthritis with the maximum degree of satisfaction of veterinarians and dog owners. Instructions for use of the drug previcox Storage As the active substance contains: firocoxib – 24% (depending on the dosage of 57 mg and 227 mg per tablet, respectively), excipients: lactose monohydrate – 49.3%, microcrystalline cellulose -15%, hydroxypropylcellulose – 3.0%, croscarmellose – 2.8%, colloidal silicon dioxide – 0.5%, flavoring and aromatic substances (flavor with the taste of smoked meat “Chartor Hickory smoke flavor” and caramel) – 5%, pigments – yellow and red iron oxides – 0.4%. In appearance, the drug is a brown tablet, round, convex, on one side of the tablet cutting and engraving “M and dosage”. Store the drug in a closed package of the manufacturer, separately from food and feed, in a dry place, protected from direct sunlight, at a temperature of 0 ° C to 30 ° C. Shelf life of the drug under storage conditions – 4 years from the date of manufacture. Unused half of the tablet can be stored in a blister for no more than 7 days. Pharmacological properties Previkoks tablets of 57 mg and 227 mg belong to the group of nonsteroidal anti-inflammatory drugs. Firocoxib, which is part of the drug, is a selective inhibitor of cyclooxygenase-2 (COX-2), selectively disrupts the formation of prostaglandins involved in the formation of the inflammatory reaction, inhibits the exudative and proliferative phases of inflammation. It acts mainly in the inflammatory focus and has almost no effect on the production of prostaglandins, which regulate renal blood flow and the integrity of the mucous membrane of the gastrointestinal tract. Has analgesic, anti-inflammatory and antipyretic effects. After oral administration to dogs in the recommended dose of firocoxib is rapidly absorbed, the maximum concentration in the blood is reached after 1.25 hours. The elimination half-life is 8 hours. Firocoxib is almost completely bound to blood proteins, metabolized in the liver, excreted in bile through the intestine. Previkoks tablets of 57 mg and 227 mg according to the degree of impact on the body are moderately dangerous substances (hazard class 3 according to GOST 12.1.007-76), in the recommended doses do not have sensitizing, teratogenic and embryotoxic effects. The order of application and dosage Previkoks tablets of 57 mg and 227 mg are prescribed to dogs as anti-inflammatory, analgesic and antipyretic in the treatment of osteoarthritis, as well as after orthopedic, dental and soft tissue surgeries. Contraindication to use is the increased individual sensitivity of the animal to the components of the drug (including in the anamnesis). It is forbidden to use the drug to pregnant and lactating previcox